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  Indian J Med Microbiol
 

Figure 1: Clinical images of an eye with intraocular retinoblastoma (in a patient who had the left eye enucleated for advanced intraocular retinoblastoma) that was salvaged by EBRT after failure of combined chemotherapy and focal therapy. Fundus examination of the right eye at diagnosis showed intraocular retinal tumor with total retinal detachment (a + b). After 6 cycles of carboplatin, vincristine, and etoposide chemotherapy combined with transpupillary thermotherapy and cryotherapy, the tumor responded by shrinkage and calcifications (c + d). Residual active tumors were not controlled at 2 different quadrants; inferotemporal (e) and superonasal (f) after additional 3 sessions of focal treatment by triple freeze-thaw cryotherapy, therefore, EBRT was applied. No tumor activity was seen over 2-year follow-up postsalvage EBRT (g + h)

Figure 1: Clinical images of an eye with intraocular retinoblastoma (in a patient who had the left eye enucleated for advanced intraocular retinoblastoma) that was salvaged by EBRT after failure of combined chemotherapy and focal therapy. Fundus examination of the right eye at diagnosis showed intraocular retinal tumor with total retinal detachment (a + b). After 6 cycles of carboplatin, vincristine, and etoposide chemotherapy combined with transpupillary thermotherapy and cryotherapy, the tumor responded by shrinkage and calcifications (c + d). Residual active tumors were not controlled at 2 different quadrants; inferotemporal (e) and superonasal (f) after additional 3 sessions of focal treatment by triple freeze-thaw cryotherapy, therefore, EBRT was applied. No tumor activity was seen over 2-year follow-up postsalvage EBRT (g + h)