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  Indian J Med Microbiol
 

Figure 1: Multi-cavitary ciliary body melanoma in a 66-year-old Caucasian female. (a) Slit lamp photograph of the right eye showing temporal iris bulge suggestive of ciliary body mass. (b) Ultrasound biomicroscopy revealed a 4 mm thick ciliary body mass with solid tumor posteriorly as well as multiple acoustically empty cavities. (c) Gross pathology showed empty and sparse proteinaceous fluid-filled cavities following partial lamellar scleroiridocyclectomy. Scleral base is still attached. (d) Histopathology showed solid mass in the base and large cavities in the apex (H and E, ×15). (e) Composed of low-grade amelanotic spindle-shaped melanoma cells (H and E, ×20). (f) The tumor cells showed positive staining with melanoma marker microphthalmia transcription factor-2. Note that the empty cavities are lined by tumor cells and not epithelial cells (H and E, ×20)

Figure 1: Multi-cavitary ciliary body melanoma in a 66-year-old Caucasian female. (a) Slit lamp photograph of the right eye showing temporal iris bulge suggestive of ciliary body mass. (b) Ultrasound biomicroscopy revealed a 4 mm thick ciliary body mass with solid tumor posteriorly as well as multiple acoustically empty cavities. (c) Gross pathology showed empty and sparse proteinaceous fluid-filled cavities following partial lamellar scleroiridocyclectomy. Scleral base is still attached. (d) Histopathology showed solid mass in the base and large cavities in the apex (H and E, ×15). (e) Composed of low-grade amelanotic spindle-shaped melanoma cells (H and E, ×20). (f) The tumor cells showed positive staining with melanoma marker microphthalmia transcription factor-2. Note that the empty cavities are lined by tumor cells and not epithelial cells (H and E, ×20)