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REVIEW ARTICLE
Year : 2021  |  Volume : 14  |  Issue : 2  |  Page : 74-77

Working up a child with demyelinating optic neuritis: Striking a balance!


1 Nimmagadda Prasad Childrenfs Eye Care Centre, Child Sight Institute, Department of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology, L V Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India
2 Jasti V Ramanamma Childrenfs Eye Care Centre, Child Sight Institute, Department of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology, L V Prasad Eye Institute, Hyderabad, Telangana, India

Correspondence Address:
Dr. Virender Sachdeva
Nimmagadda Prasad Children's Eye Care Centre, Child Sight Institute, Visakhapatnam, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ojo.ojo_105_21

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Pediatric optic neuritis (PON) is one of the commonest causes of acute vision loss in children. Although it might often be postinfectious or postvaccination, recent understanding and available evidence suggest that it can be the first manifestation of a neuro-inflammatory syndrome such as multiple sclerosis, neuromyelitis optica spectrum disorder, acute disseminated encephalomyelitis or myelin oligodendrocyte glycoprotein associated optic neuritis. Therefore, neuroimaging, serological testing, cerebrospinal fluid analysis, testing for various systemic autoimmune conditions become a part of the workup. However, this can be exhaustive and expensive, especially in countries with limited access to health insurance. Many recent studies suggest that neuroimaging and few clinical features can provide clues to the underlying etiology. However, serological tests can provide a confirmatory evidence. Therefore, in this mini-review, we propose a balanced approach to the evaluation of PON, based on the available literature emanating in the last decade.


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