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Year : 2015  |  Volume : 8  |  Issue : 2  |  Page : 92-96

Morphological and functional outcomes following modified early treatment diabetic retinopathy study laser in diabetic macular edema

1 Department of Shri Bhagwan Mahavir Vitreoretinal, 18, Sankara Nethralaya, Chennai, Tamil Nadu, India
2 Department of Optometry, Elite School of Optometry, No.8, St. Thomas Mount, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Rajiv Raman
Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, College Road, Chennai - 600 006, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-620X.159252

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Aim: The aim was to report morphological and functional outcomes following modified early treatment diabetic retinopathy study (ETDRS) laser in diabetic macular edema (DME). Materials and Methods: Structural and functional changes using spectral domain optical coherence tomography (OCT) and microperimetry (MP) were studied before and 4 months after laser in 37 eyes with clinically significant macular edema (ME) requiring modified ETDRS laser treatment. Paired t-test was used to compare pre and postlaser outcomes P < 0.05 was considered statistically significant. Results: Central foveal thickness showed a significant reduction after laser P = 0.004. There was a significant reduction in mean retinal thickness (MRT) and retinal volume in all the quadrants of ETDRS except for the temporal and nasal quadrants in outer 6 mm ring. Maximum reduction in MRT was seen in eyes with DME having neurosensory detachment (382.66 μ to 292.61 μ). Retinal sensitivities reduced in all quadrants following laser, however, fixation patterns showed improvements. The change in VA was positively correlated to change in MRT (r = 0.468, P = 0.032). Conclusion: Laser not only causes structural benefits such as reduction of retinal thickness and volume, it also causes improvement of fixation patterns.

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