| ORIGINAL ARTICLE |
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| Year : 2013 | Volume
: 6
| Issue : 2 | Page : 92-95 |
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Selective laser trabeculoplasty: Does energy dosage predict response?
Larissa Habib1, James Lin1, Tamara Berezina1, Bart Holland2, Robert D Fechtner1, Albert S Khouri1
1 Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ, USA
2 Rutgers New Jersey Medical School, Newark, NJ, USA
Correspondence Address:
Albert S Khouri
MD, Institute of Ophthalmology and Visual Science, 90 Bergen St., Suite 6100, Newark, NJ, 07103
USA
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0974-620X.116635
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Background: Selective laser trabeculoplasty (SLT) is a widely used treatment for open angle glaucoma, producing sustained reductions of intraocular pressure (IOP). The aim of this study was to evaluate the long-term relationship between SLT energy dosage and IOP reduction.
Materials and Methods: A retrospective review was performed for patients receiving primary SLT therapy, with inclusion of subjects treated with 360° of SLT. Energy settings were collected upon treatment and IOP was collected at baseline up to 36 months. Pearson's correlation coefficient was used to determine whether there was a significant correlation between SLT energy and IOP reduction at all time points. Kaplan-Meier analysis with log-rank test was performed to determine the differences in IOP reduction ≥20% from baseline among those treated with low (<85 mJ), medium (85-105 mJ), and high (>105 mJ) energy SLT.
Results: A total of 104 eyes (75 patients) were included. The mean total SLT energy was 93.73 mJ (standard deviation (SD) = 21.83 mJ, range: 34.4-122 mJ). A significant positive correlation (P ≤ 0.05) between the amount of energy delivered and IOP reduction was found at all time points. Log-rank test showed a significant difference in IOP reduction ≥20% from baseline between the three energy groups, with low energy patients experiencing failure at an earlier time (P = 0.05).
Conclusions: Within the range of total energy examined, there is a positive correlation between total energy used and amount of pressure reduction achieved at up to 3 years of follow-up. This may be useful in determining the optimal energy dosage for maximum effect for patients receiving SLT. |
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