About OJO | Search | Ahead of print | Current Issue | Archives | Author Instructions | Reviewer Guidelines | Online submissionLogin 
Oman Journal of Ophthalmology Oman Journal of Ophthalmology
  Editorial Board | Subscribe | Advertise | Contact
https://www.omanophthalmicsociety.org/ Users Online: 78  Wide layoutNarrow layoutFull screen layout Home Print this page  Email this page Small font size Default font size Increase font size

 Table of Contents    
Year : 2012  |  Volume : 5  |  Issue : 3  |  Page : 175-180  

A retrospective analysis of the first Yemeni experience on Artisan phakic intraocular lens for the treatment of moderate and high myopia

1 Department of Eye, Faculty of Medicine and Health Sciences, Sana'a University and Refractive Surgery Unit, Magrabi Eye Hospital, Sana'a, Yemen
2 Refractive Surgery Unit, Magrabi Eye Hospital, Sana'a, Yemen

Date of Web Publication15-Jan-2013

Correspondence Address:
Mahfouth A Bamashmus
P. O. Box 19576, Sana'a
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-620X.106098

Rights and Permissions

Objectives: To evaluate the outcome and safety of the iris-fixated Artisan phakic intraocular lens (PIOL) for the correction of moderate and high myopia.
Materials and Methods: A retrospective non-controlled clinical study of the data of patients who underwent Artisan PIOLs between March 2006 and July 2008 was evaluated. Pre-operative examination included age, gender, refraction, uncorrected (UCVA) and best spectacle corrected (BSCVA) visual acuity, predictability and safety were analyzed. Post-operative time course ranged from 12 to 36 months.
Results: An Artisan myopia lens was implanted in 62 eyes of 39 patients. The mean pre-operative spherical equivalent (SE) was −13.17 ± 5.62 D. The pre-operative myopia ranged from −4.5 to −24 D. Mean patient age was 25.44 ± 5.22 years. At last follow-up visit, residual SE was within ±1.00 D in 36 eyes (58.1%) and ±2.00 D in 56 eyes (90.3%). In the last visit UCVA was equal to or better than pre-operative BSCVA in 57 (91.9%) of the eyes. One eye (1.6%) lost one Snellen line, three eyes (4.8%) lost two or more Snellen lines and one eye lost vision (1.6%). Post-operative complications included anterior chamber reaction in one eye, rise in intraocular pressure in two eyes and retinal detachment in one eye.
Conclusion: When laser keratorefractive surgery is not an option, implantation of Artisan PIOL to correct moderate to high myopia results in a stable and good refractive result with few complications that must be kept in mind.

Keywords: Artisan, myopia, phakic intraocular lens, refractive surgery, Yemen

How to cite this article:
Bamashmus MA, Mohamed AA, Alakhlee HA. A retrospective analysis of the first Yemeni experience on Artisan phakic intraocular lens for the treatment of moderate and high myopia. Oman J Ophthalmol 2012;5:175-80

How to cite this URL:
Bamashmus MA, Mohamed AA, Alakhlee HA. A retrospective analysis of the first Yemeni experience on Artisan phakic intraocular lens for the treatment of moderate and high myopia. Oman J Ophthalmol [serial online] 2012 [cited 2023 Mar 31];5:175-80. Available from: https://www.ojoonline.org/text.asp?2012/5/3/175/106098

   Introduction Top

Contact lenses and spectacles are the most common ways of correcting myopia; however, they have their own limitations. Laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) are the most widely performed laser keratorefractive surgery procedures for the correction of myopia. [1],[2] The results of laser keratorefractive surgeries are not good for myopia more than 10.0 D especially with glare and halo due to smaller optical zone. [3] the risk of keratectasia due to thinning of cornea [4] and the decrease in the best spectacle corrected visual acuity (BSCVA). [5]

At our refractive surgery unit, the rejection rate for LASIK stands at 25.4% [6] and for LASIK and PRK stands at 21%, [7] the most common reasons for rejection are suboptimal corneal thickness, high myopia, keratoconus and forme fruste keratoconus (keratoconus suspect).

Clear lens extraction (CLE) is also used to correct high myopia but it abolishes accommodation in young people and theoretically increases the chance of retinal detachment. [8]

Alternatives to the above procedures for the correction of moderate to high myopia include implantation of a phakic intraocular lens (PIOL). [9] PIOLs were introduced in the 1950s to correct refractive errors by Strampelli and Barraquer [10] and they are gaining widespread acceptance as the standard surgical procedure for moderate to high myopia. The advantages of this procedure are better quality of vision, potential reversibility of this procedure, preservation of accommodation and stability of refractive outcome. [10],[11]

They are grouped into three major subtypes : Iris-fixated, angle supported and posterior chamber PIOLs. [10] Angle supported has been abandoned in favor of the other PIOLs because they are associated with high rates of iris and iridocorneal angle complication and corneal endothelial loss. [11] Iris-fixated or iris-claw Artisan phakic IOLs (Ophtec BV, Groningen, The Netherlands) is the mostly used and provide satisfactory results in refractive surgery for correction of myopia, hyperopia and astigmatism. [12],[12],[13],[14]

This retrospective non-controlled clinical study was performed to evaluate the clinical outcome and refractive results of iris-fixated Artisan PIOLs implanted in the management of patients with moderate to high myopia. To our knowledge, there is no Yemeni data published on iris-supported Artisan PIOLs (PubMed Search).

   Materials and Methods Top

All eyes that were implanted with Artisan phakic IOL (Ophtec BV, Groningen, The Netherlands) at our refractive surgery unit in Yemen Magrabi Hospital in Sana'a between March 2006 and July 2008 were retrospectively analyzed.

These procedures were offered to patients seeking refractive surgery and were unsuitable for laser keratorefractive surgery due to suboptimal corneal thickness, suspicious corneal topography or high refractive error. Patient's age chosen was above 18 years with stable refractive error for at least 1 year, anterior chamber depth (ACD) more than 2.8 mm from the endothelium and intraocular pressure (IOP) less than 21 mmHg. This procedure was not offered for patients with glaucoma, uveitis, macular and retinal dystrophies or diseases. A signed written informed consent was taken from all patients before the procedure.

Pre-operative ocular examination included uncorrected visual acuity (UCVA), BSCVA before and after surgery, slitlamp examination (Haag Streit, Bern, Switzerland), Goldmann applanation tonometry (Haag Streit, Bern, Switzerland), corneal topography (Topography Modeling System -2 Topography system, Tomey Co.), pachymetry (Nidek UP-1000 Ultrasonic pachymeter, Gamagori, Japan) and ACD measurement (Nidek Co, Gamagori, Japan),

The pre-operative refraction was performed with and without cycloplegia (cyclopentolate hydrochloride 1.0%, Alcon-Cusi, Spain). Dilated fundus examination was done by the refractive surgeon and suspicious retinal cases were referred to the vitreoretinal unit.

The Artisan myopia lenses used in our patients were convex-concave (models 206 and 204) iris fixated IOLs, designed by Jan Worst and manufactured by Ophtec BV, Groningen, The Netherlands. All eyes were implanted with these models except one eye was implanted with toric Artisan and three eyes with Artiflex (foldable form of Artisan). The overall length of the lens is 8.5 mm. The optic is manufactured in diameters of 5 and 6 mm. The 6 mm lens is available from −3 to −15.5 diopter (D) in half D steps and the 5 mm lens from −3 to −23.0 D in half D steps. Both lens designs are exactly the same and differ only in optical diameter and effective optical zone size. The height of either lens does not exceed 0.95 mm.

The power of the lens was calculated with the Van der Heijde formula and was based on the refractive power of the cornea (mean corneal curvature, K) and the patients' spherical equivalent (SE) refractive error (spectacle correction at 12.0 mm vertex).

One drop of 2% pilocarpine was instilled in the morning and 30 min prior to surgery. The surgery was performed under general anesthesia in all patients. Two side port incisions were made at 2 o'clock and 11 o'clock positions for the superior approach and at 1 o'clock and 5 o'clock positions for the temporal approach.

Intraocular acetylcholine chloride was injected (Miostat, Alcon, USA). The anterior chamber was filled with sodium hyaluronate solution (Oculocrom, Croma pharma Gmbh, Austria). A clear corneal limbal incision of 5 to 6 mm was made at 12 o'clock or 3 o'clock and in the cases of Artiflex a 3.2 mm limbal incision was made.

The Artisan myopia lens was introduced toward the 6 o'clock or 9 o'clock position, the lens was rotated using Sinskey hook, it was then held with a Shepard forceps (Katena Co., USA) at the outer part of the optic and the enclavation needle (Ophtec BV, Groningen, The Netherlands) passed through the paracenteces and iris tissue was enclavated. A peripheral iridectomy (PI) was performed with Vannas scissors (Katena Co., USA). After removing the viscoelastic from the anterior chamber the wound was closed with 10/0 nylon (Aurolab Co., India). Subconjunctival dexamethasone and gentamicin was given at the end of the procedure and the eye was padded. If the surgery was required to be done for both eyes, the surgery was done on the same session or on different sessions according to the patient request.

Post-operatively, prednisolone acetate eye drops 1% (Predforte, Allergan, Irvine, USA) four times daily tapering over four weeks and ciprofloxacin 0.3% (Ciloxan, Alcon, USA) eye drops four times daily for four weeks were used.

Follow-up examinations were performed in 1 day, 3 days, 1 week, 4 weeks, 3 months, 6 months and 12 months and annually thereafter. Patients with complications were examined more frequently.

Statistically significant differences between the means of the data samples were determined by Pearson correlation. We calculated the percentages for the data by utilizing the Excel 2007 program. Visual acuity (VA) data was converted to logMAR equivalents for statistical analyses and logMAR statistics were converted back into Snellen equivalents for the presentation of results.

The study was approved by the Research and Ethics committee of Yemen Magrabi Hospital, and the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional), and with the Helsinki Declaration of 1975, as revised in 2000. The risk of the surgery was fully explained to the patients in accordance with the Helsinki Declaration, and written informed consent was obtained.

   Results Top

The study population includes 62 eyes of 39 patients with follow-up for at least 12 months but some were followed for up to 36 months. Age ranged from 18 to 36 years with a mean age of 25.44 ± 5.23 years [Table 1]. It included 14 males (35.9%) and 25 females (64.1%) and 23 patients (59.0%) had the surgery to both eyes. Majority of eyes had the superior wound approach (53.2%). Corneal topography details are shown in [Table 2].
Table 1: Patients characteristics of the Artisan study in Yemen (2006-2008)

Click here to view
Table 2: Surgical characteristics of the Artisan study in Yemen (2006-2008)

Click here to view

Mean SE refraction was −13.17 ± 5.62 D. Pre-operative myopia ranged from −4.50 to −24.00 D. The ACD ranged from 2.80 to 3.93 mm and the mean ACD was 3.09 ± 0.34 mm. The axial length (AL) ranged from 22.61 to 32.50 mm and the mean AL was 28.03 ± 2.18 mm. The mean Artisan power implanted was −13.80 ± 4.79 D (range: −4.50 to −22.50 D). The mean pre-operative astigmatism was 1.38 ± 1.11 D (range 0.25 to 5.00 D). By 12 months, the mean post-operative astigmatism was 0.86 ± 0.72 D (P = 0.93). [Table 3] shows the pre-operative characteristics for treated eyes.
Table 3: Pre-operative details of the Artisan study in Yemen (2006-2008)

Click here to view

At 12 months, the UCVA was 20/20 or better in 2 eyes (3.2%), 20/30 or better in 27 eyes (43.55%) and 20/40 or better in 34 eyes (54.84%). 34 eyes (54.8%) had UCVA of 20/40 or better. Twenty eight eyes (45.2%) had refraction within ±0.50 D, 36 eyes (58.1%) within ±1.00 D, 56 eyes (90.3%) within ±2.00 D [Figure 1].
Figure 1: Post-operative spherical equivalent refractive outcome

Click here to view

In terms of safety, BSCVA remained the same or improved in 57 eyes (91.9%). In one eye (1.6%) there was loss of one Snellen line [Figure 2]. The mean BSCVA improved from 20/70 pre-operatively to 20/30 post-operatively (P < 0.0005 r = 0.62). The Snellen equivalent medians for pre-operative BSCVA, post-operative UCVA and post-operative BSCVA were 20/50, 20/40 and 20/30 respectively.
Figure 2: Change in post-operative spectacle corrected visual acuity

Click here to view

The predictability was better in the lower-level of myopia. Of the 27 eyes with myopia between −5 to −10 D, 21 (77.8%) had post-operative refraction within ±1.00 D. In eyes with myopia ranging between −10.5 and −20 D, 23 out of 30 eyes (76.7%) had post-operative refraction within ±1.00 D and in those with myopia between −20.5 and −24 D, 4 out of 5 eyes (80.0%) were within ±1.00 D.

Post-operative complications encountered in the study group were; one eye developed anterior uveitis; one eye developed hyphema; and two eyes developed increase in IOP and were given anti-glaucoma medications [Table 2]. No eye developed dislocation or decentration of the Artisan lens, readjustment of centration, resuturing due to shallow anterior chamber or opening of the PI surgically or by YAG laser. One eye developed spontaneous rhegmatogenous retinal detachment (RRD) and was treated by our vitreoretinal surgeon but unfortunately developed cataract, which was treated with phacoemulsification and removal of the artisan lens but the eye developed severe uveitis and cylctitic membrane and ended with phthisis bulbi with vision of no perception of light [Table 2] and [Figure 2]. Two patients reported night glare/halo.

   Discussion Top

Moderate and high myopia are treated either by laser in situ keratomileusis (LASIK) or PIOL. LASIK results for myopia of more than −10.0 D are poor because of the risk of ectasia and poor visual quality. [15],[16]

This study replicates the efficacy and safety of Artisan PIOL implantation for the surgical management of moderate to high myopia. [12],[12],[13],[14],[17],[18],[19],[20],[21]

In our study, the main outcome measure used to assess the effectiveness and safety of the artisan PIOL was uncorrected post-operative visual acuity (UCVA) and the maintenance or improvement in BSCVA compared to pre-operative BSCVA [Figure 2]. BSCVA remained the same or improved in 57 eyes (91.9%). The mean BSCVA improved from 20/70 pre-operatively to 20/30 post-operatively (P < 0.0005; r = 0.62). This improvement could be due to increase in optical quality of lenses and also magnification of lenses due to position of Artisan lenses relative to glasses.

At twelve months, 34 eyes (54.8%) achieved UCVA of 20/40 or better, which is better than an Iranian study (52%) (22) but less compared to 73.4% in Landesz et al. study; [17] 75% in the Indian study; [20] 79.6% in Benedetti et al. study. [18]

Other outcome measures used in this study included post-operative refraction within ±1.00 D, ±2.00 D and post-operative astigmatism. In our series, 36 eyes (58.1%) had post-operative refraction within ±1.00 D and this was comparable to some studies and worse than other published series. A refractive outcome within ±1.00 D was variably reported to be achieved in 60% (18), 68% (17), 68% (22), 82% (15), 90% (20), 93% (19). Post-operative refraction within ± 2.00 D was 90.3% which is similar to other studies of 92%. [22] The predictability was better in the lower-level of myopia, where 77.8% of the low myopes had post-operative refraction within ±1.00 D.

Mean pre-operative astigmatism was 1.38 ± 1.11 D and by twelve months, the astigmatism had reduced to 0.86 ± 0.72 D (P = 0.93). This was comparable to other studies, where pre-operative astigmatism of 1.12 ± 0.8 D had reduced to 0.82 ± 0.62 D. [23]

In this study, BSCVA remained the same or improved in 91.9%. One eye (1.6%) had loss of one Snellen line of VA and three eyes (4.8%) lost two or more Snellen lines. In comparison, the US food and drug administration (FDA) study showed that 5% of eyes lost one line and 95% had either no loss or gained one line or more. [19] In the Indian study, 11.6% lost one Snellen line and none had loss of two or more Snellen lines. [20] The mean BSCVA improved from 20/70 pre-operatively to 20/30 post-operatively (P < 0.0005 r = 0.62).

Several studies with Artisan iris-fixated lens implantation reported endothelial damage and cell loss over the years, [24] while in other studies no endothelial cell loss [21] or low endothelial cell loss was encountered. [20] We do not have specular microscope in Yemen and endothelial cell count was not studied.

Intra-operatively six eyes encountered hyphema, three eyes iris prolapse but no eye had traumatic cataract. All eyes that had surgical PI during surgery but post-operatively two eyes had IOP rise. In the two eyes the IOP was controlled medically and they were off medication within one month. Retained viscoelastics after implantation of PIOL or steroid responsiveness, could be a possible cause of IOP rise. [25] Intraocular pressure rise varied in various studies reaching up to 10% (20). Post-operative iritis was noted in one eye. Inflammatory reaction in various studies ranged from 0% (17), 3.3% (20) and as high as 45%. [21]

Glare or halos, which affect night vision and driving, is an important consideration in PIOL implantation. In our series, two patients experienced this complication, but did not bother them. Probably because Yemeni eyes have smaller pupil size compared to Caucasians, can be an explanation of why our patients did not complain of glare or halos. Other studies reported glare/haloes of 8%. [18]

An important sight threatening complication associated with PIOLs is retinal detachment. We did encounter one retinal detachment and unfortunately after retinal detachment surgery developed cataract followed by severe uveitis and phthisis bulbi. Six eyes (9.7%) had prophylactic laser for retinal holes, retinal flaps or lattice degeneration. The laser was done 1-2 weeks prior to lens implantation, to ensure good adhesion. However, the efficacy of this procedure as a routine in all patients to prevent post-operative retinal detachment is not documented. [26] Retinal detachment after myopia can be related to the disease itself or to the PIOL but it has not been proven. [27],[28]

Other complications of Artisan PIOL are rare. Cataract development, [29] PIOL dislocation, [20] corneal decopmensation, [30] change in configuration of pupil, [31] vitreous hemorrhage, [32] choroidal neovascularization, [33] endophthalmitis [34] were not seen in our group of patients.

The main limitation of this study is the retrospective data and all the data were collected from a single center. Other limitations are absence of evaluation of endothelial cell count pre-operatively and post-operatively because of the unavailability of specular microscope in Yemen.

   Conclusion Top

The results of this study support the efficacy and safety of Artisan PIOL as a refractive surgical procedure for correction of moderate to high myopia. Both UCVA and BSCVA improved over the follow-up period with a few complications. Only one unfortunate patient lost his vision in one eye due to retinal detachment, which did not respond well to retinal detachment surgery.

This surgical technique has good results in moderate to high myopic patients that cannot be corrected by other methods but longer follow-up is necessary to monitor for other complications, namely cataract.

   Acknowledgement Top

We thank administrators and staff of Yemen Magrabi Hospital for permitting us to conduct this study. They assisted and contributed in the patient's care in our study. Lastly, we appreciate the efforts and cooperation of all patients they extended to us in this study.

   References Top

1.Dirani M, Couper T, Yau J, Ang EK, Islam FM, Snibson GR, et al. Long-term refractive outcomes and stability after excimer laser surgery for myopia. J Cataract Refract Surg 2010;36:1709-17.   Back to cited text no. 1
2.Alió JL, Muftuoglu O, Ortiz D, Pérez-Santonja JJ, Artola A, Ayala MJ, et al. Ten-year follow-up of laser in situ keratomileusis for myopia of up to-10 diopters. Am J Ophthalmol 2008;145:46-54.   Back to cited text no. 2
3.Fan-Paul NI, Li J, Miller JS, Florakis GJ. Night vision disturbances after corneal refractive surgery. Surv Ophthalmol 2002;47:533-46.  Back to cited text no. 3
4.Randleman JB, Russell B, Ward MA, Thompson KP, Stulting RD. Risk factors and prognosis for corneal ectasia after LASIK. Ophthalmology 2003;110:267-75.  Back to cited text no. 4
5.Doughman DJ, Hardten DR. Loss of vision after laser in situ keratomileusis. Eye Contact Lens 2003;29:S135-8.  Back to cited text no. 5
6.Bamashmus M, Saleh MF, Abdulrahman M, Al-Kershy N. Reasons for not performing LASIK in refractive surgery candidates in Yemen. Eur J Ophthalmol 2010;20:858-64.  Back to cited text no. 6
7.Bamashmus MA, Saleh MF, Awadalla MA. Reasons for not performing keratorefractive surgery in patients seeking refractive surgery in a hospital-based cohort in "yemen". Middle East Afr J Ophthalmol 2010;17:349-53.  Back to cited text no. 7
[PUBMED]  Medknow Journal  
8.Fernández-Vega L, Alfonso JF, Villacampa T. Clear lens extraction for the correction of high myopia. Ophthalmology 2003;110:2349-54.  Back to cited text no. 8
9.Huang D, Schallhorn SC, Sugar A, Farjo AA, Majmudar PA, Trattler WB, et al. Phakic intraocular lens implantation for the correction of myopia: A report by the American Academy of Ophthalmology. Ophthalmology 2009;116:2244-58.  Back to cited text no. 9
10.Lovisolo CF, Reinstein DZ. Phakic intraocular lenses. Surv Ophthalmol 2005;50:549-87.  Back to cited text no. 10
11.Kohnen T, Baumeister M, Cichocki M. Intraocular lenses for the correction of refraction errors. Part 1: Phakic anterior chamber lenses. Ophthalmologe 2005;102:1003-7.  Back to cited text no. 11
12.Qasem Q, Kirwan C, O'Keefe M. 5-year prospective follow-up of Artisan phakic intraocular lenses for the correction of myopia, hyperopia and astigmatism. Ophthalmologica 2010;224:283-90.  Back to cited text no. 12
13.Güell JL, Morral M, Gris O, Gaytan J, Sisquella M, Manero F. Five-year follow-up of 399 phakic Artisan-Verisyse implantation for myopia, hyperopia, and/or astigmatism. Ophthalmology 2008;115:1002-12.  Back to cited text no. 13
14.Tahzib NG, Bootsma SJ, Eggink FA, Nuijts RM. Functional outcome and patient satisfaction after Artisan phakic intraocular lens implantation for the correction of myopia. Am J Ophthalmol 2006;142:31-9.  Back to cited text no. 14
15.Malecaze FJ, Hulin H, Bierer P, Fournié P, Grandjean H, Thalamas C, et al. A randomized paired eye comparison of two techniques for treating moderately high myopia: LASIK and artisan phakic lens. Ophthalmology 2002;109:1622-30.  Back to cited text no. 15
16.El Danasoury MA, El Maghraby A, Gamali TO. Comparison of iris-fixed Artisan lens implantation with excimer laser in situ keratomileusis in correcting myopia between -9.00 and -19.50 diopters: A randomized study. Ophthalmology 2002;109:955-64.  Back to cited text no. 16
17.Landesz M, van Rij G, Luyten G. Iris-claw phakic intraocular lens for high myopia. J Refract Surg 2001;17:634-40.  Back to cited text no. 17
18.Benedetti S, Casamenti V, Marcaccio L, Brogioni C, Assetto V. Correction of myopia of 7 to 24 diopters with the Artisan phakic intraocular lens: Two-year follow-up. J Refract Surg 2005;21:116-26.  Back to cited text no. 18
19.Stulting RD, John ME, Maloney RK, Assil KK, Arrowsmith PN, Thompson VM, et al. Three-year results of Artisan/Verisyse phakic intraocular lens implantation. Results of the United States Food And Drug Administration clinical trial. Ophthalmology 2008;115:464-72.  Back to cited text no. 19
20.Senthil S, Reddy KP, Ravisankar, Srilakshmi. A retrospective analysis of the first Indian experience on Artisan phakic intraocular lens. Indian J Ophthalmol 2006;54:251-5.  Back to cited text no. 20
[PUBMED]  Medknow Journal  
21.Rahimi F, Hashemian MN, Dehsarvi B, Alipour F, Rajabi MT. Iris-supported Artisan phakic intraocular lenses for treatment of moderate to high myopia. Iranian J Ophthalmol 2008;20:37-41.  Back to cited text no. 21
22.Siatiri H, Mohammadi SF, Nasab MM, Abdollahinia T, Siatiri N. Outcome of iris-claw phakic intraocular lens implantation for high myopia; A subspecialty training setting. Iranian J Ophthalmol 2009;21:21-8.  Back to cited text no. 22
23.Maloney RK, Nguyen LH, John ME. Artisan phakic intraocular lens for myopia: Short-term results of a prospective, multicenter study. Ophthalmology 2002;109:1631-41.  Back to cited text no. 23
24.Benedetti S, Casamenti V, Benedetti M. Long-term endothelial changes in phakic eyes after Artisan intraocular lens implantation to correct myopia: Five-year study. J Cataract Refract Surg 2007;33:784-90.  Back to cited text no. 24
25.Aguilar-Valenzuela L, Lleó-Pérez A, Alonso-Muñoz L, Casanova-Izquierdo J, Pérez-Moltó FJ, Rahhal MS. Intraocular pressure in myopic patients after Worst-Fechner anterior chamber phakic intraocular lens implantation. J Refract Surg 2003;19:131-6.  Back to cited text no. 25
26.Aylward GW. Screening for retinal detachment. J Med Screen 2001;8:116-8.  Back to cited text no. 26
27.Rosen E. Risk management for rhegmatogenous retinal detachment following refractive lens exchange and phakic IOL implantation in myopic eyes. J Cataract Refract Surg 2006;32:697-701.  Back to cited text no. 27
28.Georgalas I, Petrou P, Papaconstantinou D, Koutsandrea C, Ladas I. Bilateral giant tear-associated retinal detachment following Artisan phakic intraocular lens implantation for correction of moderate myopia. Acta Ophthalmol 2010;88 :e0 143-4.  Back to cited text no. 28
29.Chen LJ, Chang YJ, Kuo JC, Rajagopal R, Azar DT. Metaanalysis of cataract development after phakic intraocular lens surgery. J Cataract Refract Surg 2008;34:1181-200.  Back to cited text no. 29
30.Kim M, Kim JK, Lee HK. Corneal endothelial decompensation after iris-claw phakic intraocular lens implantation. J Cataract Refract Surg 2008;34:517-9.  Back to cited text no. 30
31.Dick HB, Aliyeva S, Tehrani M. Change in pupil size after implantation of an iris-fixated toric phakic intraocular lens. J Cataract Refract Surg 2005;31:302-7.  Back to cited text no. 31
32.Nuzzi G, Cantù C. Vitreous hemorrhage following phakic anterior chamber intraocular lens implantation in severe myopia. Eur J Ophthalmol 2002;12:69-72.  Back to cited text no. 32
33.Ruiz-Moreno JM, de la Vega C, Ruiz-Moreno O, Alió JL. Choroidal neovascularization in phakic eyes with anterior chamber intraocular lenses to correct high myopia. J Cataract Refract Surg 2003;29:270-4.  Back to cited text no. 33
34.Diab F, Al-Rashaed S, Al-Motowa S. Endophthalmitis after Artisan phakic intraocular lens implantation for correction of high myopia. J Refract Surg 2006;22:332-3.  Back to cited text no. 34


  [Figure 1], [Figure 2]

  [Table 1], [Table 2], [Table 3]


    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

  In this article
    Materials and Me...
    Article Figures
    Article Tables

 Article Access Statistics
    PDF Downloaded242    
    Comments [Add]    

Recommend this journal