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ORIGINAL ARTICLE
Year : 2009  |  Volume : 2  |  Issue : 1  |  Page : 23-26

Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation


1 Al-Hussein University Hospital, Al-Azhar University, Cairo-Egypt; Department of Ophthalmology, Rustaq Hospital, Rustaq, Sultanate of Oman
2 Department of Ophthalmology, Rustaq Hospital, Rustaq, Sultanate of Oman

Correspondence Address:
Mohamed A. E. Soliman Mahdy
The Ophthalmic Department, Rustaq Hospital, Post Box: 2, Postal code: 329 Rustaq, Sultanate of Oman

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-620X.48418

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Purpose: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. Design: Prospective noncomparative cohort study. Materials and Methods: Forty-two eyes of 42 patients with grade I-III primary pterygium were included in the study. Pterygium excision was performed followed by superotemporal limbal stem cells and conjunctival autograft transplantation in all cases. Recurrence of pterygium and complications within a mean follow-up period of 18.26 months (10-28 months) was studied. Results: Recurrence of pterygium occurred in two eyes (2/42; 4.75%). No significant complications were noted. Apart from re-operation in the two recurrent cases, no further surgical interventions were needed in any case. Conclusions: Limbal stem cells and conjunctival autograft transplantation is a safe and effective technique for the treatment of different grades of pterygium. It is very useful in preventing pterygium recurrence, which is a major problem in pterygium surgery.


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