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  Citation statistics : Table of Contents
   2011| January-April  | Volume 4 | Issue 1  
    Online since March 14, 2011

 
 
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CASE REPORTS
A rare case of adult onset retinoblastoma
Sunil Kumar Singh, Dipankar Das, Harsha Bhattacharjee, Jyotirmay Biswas, Ganesh Kuri, Kasturi Bhattacharjee, Hemlata Deka, Akshay Chandra Deka
January-April 2011, 4(1):25-27
DOI:10.4103/0974-620X.77659  PMID:21713237
Retinoblastoma usually manifests before five years of age. Retinoblastoma in an adult is extremely rare. Twenty-three cases of retinoblastoma in adults 20 years or older have been reported in world literature. We report a case of adult onset retinoblastoma in a 29-year-old female. Our patient had unilateral endophytic retinoblastoma with vitreous seeds and calcification on ultrasonography. She underwent enucleation with silicone ball implantation and the diagnosis was confirmed histopathologically. The diagnosis of retinoblastoma should be kept in mind in cases presenting with a white mass lesion of unknown etiology, in the fundus of an adult.
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REVIEW ARTICLE
Inflammatory glaucoma
Sonam A Bodh, Vasu Kumar, Usha K Raina, B Ghosh, Meenakshi Thakar
January-April 2011, 4(1):3-9
DOI:10.4103/0974-620X.77655  PMID:21713239
Glaucoma is seen in about 20% of the patients with uveitis. Anterior uveitis may be acute, subacute, or chronic. The mechanisms by which iridocyclitis leads to obstruction of aqueous outflow include acute, usually reversible forms (e.g., accumulation of inflammatory elements in the intertrabecular spaces, edema of the trabecular lamellae, or angle closure due to ciliary body swelling) and chronic forms (e.g., scar formation or membrane overgrowth in the anterior chamber angle). Careful history and follow-up helps distinguish steroid-induced glaucoma from uveitic glaucoma. Treatment of combined iridocyclitis and glaucoma involves steroidal and nonsteroidal anti-inflammatory agents and antiglaucoma drugs. However, glaucoma drugs can often have an unpredictable effect on intraocular pressure (IOP) in the setting of uveitis. Surgical intervention is required in case of medical failure. Method of Literature Search : Literature on the Medline database was searched using the PubMed interface.
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CASE REPORTS
Hemorrhagic intraretinal macrocyst: Differential diagnoses and report of an unusual case
Pukhraj Rishi, Ekta Rishi, Pratik Ranjan Sen, Tarun Sharma
January-April 2011, 4(1):28-31
DOI:10.4103/0974-620X.77660  PMID:21713238
Retinal 'cysts' may be single or multiple, ranging from two-to-ten disc diameters in size, and occur in eyes with longstanding retinal detachment. The authors describe a retinal macrocyst larger than ten disc diameters, with a blood-filled cavity, and its ultrasound findings. Improved retinal nourishment following retinal reattachment gradually reverses the process responsible for cystic degeneration, with the eventual collapse of the cyst (within days or weeks). Surprisingly, this giant cyst did not collapse for almost three years despite retinal reattachment. The internal mobile echogenic contents were suggestive of blood. The possible reason of blood in the cyst could be rupture of the retinal blood vessels in the cyst cavity. This could be a recurrent phenomenon, which did not allow the cyst to collapse. The Hemorrhagic Intraretinal Macrocyst needs to be differentiated from mimicking clinical conditions, namely, retinoschisis, choroidal melanoma, subretinal abscess, choroidal hemangioma, and the like. It could take up to a few years to collapse spontaneously, following successful retinal reattachment.
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CLINICAL IMAGES
Sudden onset isolated complete third nerve palsy due to pituitary apoplexy
Batuk Diyora, Naren Nayak, Sanjay Kukreja, Hanmant Kamble
January-April 2011, 4(1):32-34
DOI:10.4103/0974-620X.77661  PMID:21713240
  1 4,380 353
Congenital bilateral ectropion in lamellar ichthyosis
Chandana Chakraborti, Partha Tripathi, Gautam Bandopadhyay, Dayal Bandhu Mazumder
January-April 2011, 4(1):35-36
DOI:10.4103/0974-620X.77662  PMID:21713241
  1 5,946 458
Retinal pigment epithelial changes after trypan blue-assisted internal limiting membrane peeling for idiopathic macular hole
Pukhraj Rishi, Ekta Rishi, Abhishek Kothari
January-April 2011, 4(1):37-38
DOI:10.4103/0974-620X.77663  PMID:21713242
  1 3,635 345
CLINICAL QUIZ
67-year-old male with right eye discharge
Anya A Trumler
January-April 2011, 4(1):39-39
DOI:10.4103/0974-620X.77664  PMID:21713243
  - 2,627 271
EDITORIAL COMMENTARY
Cortical visual impairment in children - A new challenge for the future?
Meenakshi Swaminathan
January-April 2011, 4(1):1-2
DOI:10.4103/0974-620X.77654  PMID:21713233
  - 2,747 473
LETTERS TO THE EDITOR
Optic nerve infiltration in relapse of acute lymphoblastic leukemia
Mohammad Javed Ali, Santosh G Honavar
January-April 2011, 4(1):40-40
DOI:10.4103/0974-620X.77665  PMID:21713244
  - 3,243 358
Combined posterior flap and anterior suspended flap external dacryocystorhinostomy
Ved Prakash Gupta, Pragati Gupta, Rigved Gupta
January-April 2011, 4(1):40-41
DOI:10.4103/0974-620X.77666  PMID:21713245
  - 2,166 289
ORIGINAL ARTICLES
Combined intravitreal bevacizumab with phacoemulsification in visually significant cataract and visually significant exudative maculopathy
Ahmad Mansour, Ziad F Bashshur, Tarek A Sibai, Abla Mehio-Sibai, Rola N Hamam
January-April 2011, 4(1):10-16
DOI:10.4103/0974-620X.77656  PMID:21713234
Purpose : We investigated the visual outcome of combined phacoemulsification with intravitreal bevacizumab, in eyes with dense cataract and visually significant exudative maculopathy. Materials and Methods : Prospective longitudinal pilot study of consecutive patients treated by two surgeons in 2006, using intravitreal bevacizumab at the end of phacoemulsification. The historical control group consisted of consecutive subjects with exudative maculopathy and dense cataract treated by the same surgeons with the help of phacoemulsification without intravitreal bevacizumab prior to 2006. Results : Thirty-one treated patients had the mean (SD) logMar best corrected visual acuity improving from - 1.48 (0.50) preoperatively to - 0.67 (0.38) in the first postoperative week ( p < 0.001), to - 0.64 (0.40) in the first postoperative month ( p < 0.001), and to - 0.62 (0.42) ( p < 0.001) on the last follow-up (mean 4.2 months, range 1 - 9 months). Fourteen control patients had the mean (SD) logMar best corrected visual acuity improving from - 1.78 (0.79) preoperatively, to - 0.91 (0.53) in the first postoperative week ( p < 0.001), to - 0.86 (0.45) in the first postoperative month ( p < 0.001), and to - 0.90 (0.47) ( p < 0.001) on the last follow- up (mean 19.6 months, range 1 - 49 months). Initial visual acuities, final visual acuities, and percentage of visual improvement at one month were all not significantly better in the intervention compared to the control group at one month. In the study group, the fovea was flattened at the one-month follow-up, by 90-diopter slit lamp examination and / or Optical coherence tomography. Conclusion : The combination of intravitreal bevacizumab and phacoemulsification is beneficial for maximal visual rehabilitation in the first postoperative month.
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Ocular status and functional adaptation of visually challenged children of a special school in Oman
Rajiv Khandekar, Rikin Shah, Manali Shah, Salah Al Harby, Urmi Vora, Faiza Al Balushi
January-April 2011, 4(1):17-20
DOI:10.4103/0974-620X.77657  PMID:21713235
Introduction : We assessed the ocular status and visual adaptation among children studying at a school for visually disabled children in Muscat, Oman. Materials and Methods : This descriptive study was conducted in 2009-2010. We assessed the visual and ocular status of the participants. They were interviewed to elicit the past history of eye problems and management. They also expressed their visual adaptation in their 'day-to-day' life, and their ambitions. Result : We examined and interviewed 47 participants (29 male and 18 female). The mean age of the participants was 19.7 years (Standard deviation 5.9 years). Twenty-six of them were blind since birth. Phthisical eyes, disfigured eyes and anophthalmic sockets were noted in 19, 58, and six eyes of participants. Twenty-six (55.5%) participants had visual disabilities due to genetic causes, since birth. In 13 participants, further investigations were needed to confirm diagnosis and determine further management After low vision training, 13 participants with residual vision could be integrated in the school with normal children. One participant was recommended stem cell treatment for visual restoration. Five children were advised reconstructive orbital surgery. The participants were not keen to use a white cane for mobility. Some participants, 16 / 28 (57%), with absolute blindness, were not able to read the Braille language. Singing and playing music were not very well-accepted hobbies among the participants. Nineteen participants were keen to become teachers. Conclusions : Children with visual disabilities need to be periodically assessed. The underlying causes of visual disabilities should be further explored to facilitate prevention and genetic counseling. Participants had visual adaptation for daily living and had ambitions for the future.
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Role of antimetabolites in recalcitrant idiopathic orbital inflammatory syndrome
Yamini Priya, Suneetha Nithyanandam, Manjoo S Reddy
January-April 2011, 4(1):21-24
DOI:10.4103/0974-620X.77658  PMID:21713236
Background : High-dose systemic steroids are the primary modality of treatment for idiopathic orbital inflammatory syndrome (IOIS). Occasionally patients experience a relapse of symptoms on tapering steroids or require large doses of steroid, predisposing them to the adverse effects of steroids. Aim : We present our experience with the management of three patients with recalcitrant IOIS, with immunosuppressive therapy, using antimetabolites. Materials and Methods : A retrospective review of the medical records of the patients being reported. Results: Two patients were treated with Methotrexate and one with Azathioprine for a duration of 6-24 months. Two patients were symptom-free three years after stopping the medication. One was doing well clinically with methotrexate therapy alone, when he was lost to follow-up after six months. No adverse effects of immunosuppressive therapy were encountered. Conclusion : High-dose systemic steroid therapy is the first-line treatment for IOIS, but in refractory or steroid-dependent cases, immunosuppressive therapy with antimetabolites is a safe and effective treatment alternative to steroids. However, treatment with antimetabolites warrants close monitoring for complications like bone marrow suppression and liver dysfunction, especially because long-term treatment is required.
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SELECTED ABSTRACTS
Selected Abstract

January-April 2011, 4(1):43-44
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