Oman Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 12  |  Issue : 3  |  Page : 181--185

Long term effect of panretinal photocoagulation on retinal nerve fiber layer parameters in patients with proliferative diabetic retinopathy


Meenakshi Wadhwani1, Shweta Bali2, Shibal Bhartiya3, Manish Mahabir4, Ashish Upadhaya5, Tanuj Dada6, Anu Sharma7, Sanjay Kumar Mishra8 
1 Department of Community Ophthalmology, Dr. Rajendra Prasad Centre For Ophthalmic Sciences, AIIMS, New Delhi, India
2 Department of Ophthalmology, University of Otawa, Canada
3 Glaucoma Unit, Fortis Hospital, Gurugram, Haryana, India
4 Retina Unit, Dr. Rajendra Prasad Centre For Ophthalmic Sciences, AIIMS, New Delhi, India
5 Department of Biostatics, Dr. Rajendra Prasad Centre For Ophthalmic Sciences, AIIMS, New Delhi, India
6 Glaucoma Unit, Dr. Rajendra Prasad Centre For Ophthalmic Sciences, AIIMS, New Delhi, India
7 Retina Lab, Dr. Rajendra Prasad Centre For Ophthalmic Sciences, AIIMS, New Delhi, India
8 Department of Ophthalmology, Command Hospital (Central Command), Lucknow, Uttar Pradesh, India

Correspondence Address:
Dr. Sanjay Kumar Mishra
Department of Ophthalmology, Command Hospital (Central Command), Lucknow - 226 002, Uttar Pradesh
India

PURPOSE: This study aimed to evaluate the long-term effect of panretinal photocoagulation (PRP) on the retinal nerve fiber layer (RNFL) in patients with proliferative diabetic retinopathy (PDR). METHODS: This was a prospective longitudinal cohort study examining 42 eyes of 42 patients with PDR undergoing PRP. Peripapillary RNFL thickness (RNFLT) was measured using spectral-domain optical coherence tomography at baseline, 1 year, and 3 years following PRP. RESULTS: The mean “average RNFLT” was 89.88 ± 14.26 μm at baseline, 85.75 ± 11.36 μm at 1-year follow-up, and 83.33 ± 11.96 μm at 3-year follow-up. There was a statistically significant difference in the average RNFL thickness at baseline and 1 year and 3 years after PRP. At 1-year follow-up, superior, inferior, and nasal RNFL measurements reduced significantly from baseline (P < 0.01). The reduction in RNFL remained statistically significant for superior and inferior quadrants 3 years after PRP. CONCLUSION: PRP causes a reduction in RNFL thickness until 3 years after the procedure. Caution should be exercised while interpreting peripapillary RNFL thickness scans in patients who have undergone PRP for diabetic retinopathy.


How to cite this article:
Wadhwani M, Bali S, Bhartiya S, Mahabir M, Upadhaya A, Dada T, Sharma A, Mishra SK. Long term effect of panretinal photocoagulation on retinal nerve fiber layer parameters in patients with proliferative diabetic retinopathy.Oman J Ophthalmol 2019;12:181-185


How to cite this URL:
Wadhwani M, Bali S, Bhartiya S, Mahabir M, Upadhaya A, Dada T, Sharma A, Mishra SK. Long term effect of panretinal photocoagulation on retinal nerve fiber layer parameters in patients with proliferative diabetic retinopathy. Oman J Ophthalmol [serial online] 2019 [cited 2020 Aug 12 ];12:181-185
Available from: http://www.ojoonline.org/article.asp?issn=0974-620X;year=2019;volume=12;issue=3;spage=181;epage=185;aulast=Wadhwani;type=0