Oman Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 9  |  Issue : 3  |  Page : 139--143

Combined argon laser photocoagulation and antivascular endothelial growth factor for management of macular polypoidal choroidal vasculopathy


Parveen Sen, S Vinay Kumar, Muna Bhende, Tarun Sharma 
 Department of Vitreoretina, Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India

Correspondence Address:
Parveen Sen
Department of Vitreoretina, Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, No. 18, College Road, Nungambakkam, Chennai 600 006, Tamil Nadu
India

Aim: To evaluate the efficacy of combination therapy of argon laser photocoagulation and intravitreal antivascular endothelial growth factor (VEGF) injection in idiopathic polypoidal choroidal vasculopathy (PCV) involving macula. Materials and Methods: A retrospective interventional study involving 12 eyes of 11 patients diagnosed with PCV involving the macula on indocyanine green angiography (ICGA). Intravitreal anti-VEGF was given in eyes with significant subretinal/sub retinal pigment epithelium hemorrhage or exudation. ICGA-guided focal laser was done to extrafoveal leaking polyps. Mean change in best-corrected visual acuity (BCVA) and regression of polyp as seen on ICGA were evaluated at the final follow-up. Statistical Analysis: It was done using SPSS 17.0. - Mann-Whitney test. Results: 12 eyes of 11 patients underwent argon laser with intravitreal anti-VEGF injection. Ten patients were males and one female. Mean age was 65.75 ± 5.2 years. The mean number of injections given was 3.66 ± 1.5 (2-6) per eye. Mean number of laser sessions required was 1.33 ± 0.65 (1-3) per eye. BCVA improved in 25% (n = 3), remained stable in stable in 50% (n = 6) eyes, and decreased in 25% (n = 3) eyes. The regression of polypoidal lesions on ICGA was seen in 75% (n = 9) of eyes. Persistent subretinal fluid seen in 25% (n = 3) of eyes. The mean duration of follow-up was 15.41 ± 10.27 (3-36) months. Conclusion: Combined argon laser photocoagulation with intravitreal anti-VEGF injection helps in decreasing exudation and results in stabilization of the disease with visual improvement in eyes with PCV involving macula.


How to cite this article:
Sen P, Vinay Kumar S, Bhende M, Sharma T. Combined argon laser photocoagulation and antivascular endothelial growth factor for management of macular polypoidal choroidal vasculopathy.Oman J Ophthalmol 2016;9:139-143


How to cite this URL:
Sen P, Vinay Kumar S, Bhende M, Sharma T. Combined argon laser photocoagulation and antivascular endothelial growth factor for management of macular polypoidal choroidal vasculopathy. Oman J Ophthalmol [serial online] 2016 [cited 2019 Oct 15 ];9:139-143
Available from: http://www.ojoonline.org/article.asp?issn=0974-620X;year=2016;volume=9;issue=3;spage=139;epage=143;aulast=Sen;type=0