Oman Journal of Ophthalmology

CASE REPORT
Year
: 2014  |  Volume : 7  |  Issue : 2  |  Page : 81--83

Giant leiomyoma of the ciliary body


Meredith H Remmer1, Swathi Kaliki2, Ralph C Eagle4, Carol L Shields1, Jerry A Shields1 
1 Department of Ocular Oncology, Wills Eye Institute, Thomas Jefferson University, 840 Walnut Street, 14th Floor, Philadelphia PA, 19107
2 Department of Ocular Oncology; Department of Pathology, Wills Eye Institute, Thomas Jefferson University, 840 Walnut Street, 14th Floor, Philadelphia PA, 19107

Correspondence Address:
Carol L Shields
Ocular Oncology Service, 840 Walnut Street, Suite 1440, Philadelphia, PA 19107

Leiomyoma is a rare intraocular tumor that arises from uveal smooth muscle. Herein, we report a large leiomyoma that occupied nearly 50% of the globe, closely resembling melanoma. A 40-year-old female presented with a 17 x 15 x 11 mm amelanotic ciliochoroidal mass causing visual defect in her right eye (OD). Based on transillumination features of tumor shadow and ultrasonographic features of acoustically solid mass, there was low clinical suspicion for leiomyoma or schwannoma, and a preliminary diagnosis of ciliochoroidal melanoma was rendered. Following enucleation, histopathology revealed a paucicellular tumor comprised of spindle cells, with positive immunostaining for smooth muscle actin and negative stains for melanoma markers (S-100 protein, HMB45, and MITF-2). These features were consistent with ciliochoroidal leiomyoma. Benign uveal leiomyoma can achieve an unusually large size and block light transmission on transillumination, features that simulate malignant melanoma.


How to cite this article:
Remmer MH, Kaliki S, Eagle RC, Shields CL, Shields JA. Giant leiomyoma of the ciliary body.Oman J Ophthalmol 2014;7:81-83


How to cite this URL:
Remmer MH, Kaliki S, Eagle RC, Shields CL, Shields JA. Giant leiomyoma of the ciliary body. Oman J Ophthalmol [serial online] 2014 [cited 2020 Sep 21 ];7:81-83
Available from: http://www.ojoonline.org/article.asp?issn=0974-620X;year=2014;volume=7;issue=2;spage=81;epage=83;aulast=Remmer;type=0