About OJO | Search | Ahead of print | Current Issue | Archives | Author Instructions | Reviewer Guidelines | Online submissionLogin 
Oman Journal of Ophthalmology Oman Journal of Ophthalmology
  Editorial Board | Subscribe | Advertise | Contact
https://www.omanophthalmicsociety.org/ Users Online: 213  Wide layoutNarrow layoutFull screen layout Home Print this page  Email this page Small font size Default font size Increase font size
CASE REPORT
Year : 2018  |  Volume : 11  |  Issue : 3  |  Page : 284-287

A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma


1 Department of Ophthalmology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
2 Department of Pathology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia

Correspondence Address:
Dr. Maftuhim Addenan
Department of Ophthalmology, Faculty of Medicine, University of Malaya Eye Research Centre, University of Malaya, 50603 Kuala Lumpur
Malaysia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ojo.OJO_149_2017

Rights and Permissions

Langerhans cell histiocytosis (LCH) is rarely encountered in ophthalmology practice. It is a spectrum of disorder characterized by accumulation of histiocytes in various tissues. Diagnosis is challenging as it may simulate periorbital hematoma, rhabdomyosarcoma, and neuroblastoma. We report a case of unifocal LCH with orbital extension. Diagnosis was obtained from incisional biopsy, and histopathological examination showed numerous histiocytes with eosinophilic infiltrations. The presence of Langerhans cells was confirmed by the presence of protein S-100, CD1a, and/or Langerin (CD207). Treatment depends on the degree of organ involvement. She responded well to cytotoxic drugs and steroids. This emphasized that prompt tissue diagnosis is crucial for early management.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed168    
    Printed4    
    Emailed0    
    PDF Downloaded5    
    Comments [Add]    

Recommend this journal