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CASE REPORT
Year : 2017  |  Volume : 10  |  Issue : 3  |  Page : 244-246

Localized retinal degeneration secondary to Waldenström's macroglobulinemia


1 Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India
2 Sewa Sadan Eye Hospital Trust, Behind Civil Hospital, Bhopal, Madhya Pradesh, India

Correspondence Address:
Dhanashree Ratra
Medical Research Foundation, Sankara Nethralaya, 41/18, College Road, Chennai - 600 006, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ojo.OJO_126_2016

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A 52-year-old man, treated for Waldenström's macroglobulinemia (WM), continued to experience decreased vision even after 24 months. He was evaluated using multimodal imaging and electroretinography. The retina did not show any hyperviscosity changes but revealed a yellow lesion at macula with atrophic changes causing a pattern on fluorescein angiography similar to a leopard's skin. Optical coherence tomographic imaging revealed uniformly reflective material deposited in the outer retina with degeneration of outer retinal layers. Full-field electroretinography was normal, but multifocal electroretinography revealed reduced foveal responses. This case highlights the degenerative effects of long-standing immunogammopathy maculopathy in WM.


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