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CASE REPORT
Year : 2017  |  Volume : 10  |  Issue : 3  |  Page : 232-234

Bilateral sensorineural hearing loss secondary to sympathetic ophthalmia in a human leukocyte antigen-A2 positive patient


Department of Ophthalmology, Leicester Royal Infirmary, Leicester, UK

Correspondence Address:
Konstantinos T Tsaousis
Department of Ophthalmology, Medical Retina, Leicester Royal Infirmary, Infirmary Square, Leicester, Leicestershire, LE1 5WW
UK
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ojo.OJO_170_2014

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We report a case of sympathetic ophthalmia 1 month following trauma in a 71-year-old immunocompetent female patient of Indian origin. The patient was hospitalized with signs and symptoms of meningism, ataxia, and neurosensory deafness. We explore and provide further clinical evidence in supporting the hypothesis of antigen cross-reactivity derived from tissues with common neural crest embryological background such as the uvea and cells of the labyrinth. The patient was human leukocyte antigen-A2 positive and treatment with oral steroids and cyclosporine has managed to have favorable results and control the inflammation.


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