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CLINICAL IMAGE
Year : 2016  |  Volume : 9  |  Issue : 3  |  Page : 189-190

Unusual course of interferon-related retinopathy in chronic hepatitis C


1 Department of Vitreoretina, Eye Q Hospital, New Delhi, India
2 Department of Vitreoretina, Eye Q Hospital, Hisar, Haryana, India

Correspondence Address:
Gaurav Mathur
36 Vaishali, Pitampura, New Delhi 110 034
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-620X.192308

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Interferon Alfa retinopathy usually presents as cotton wool spots, superficial hemorrhages and macular edema. We describe a rare case of severe retinopathy involving hard exudates at macula that lead to permanent visual loss in one eye. Elderly male presented with diminution of vision in right eye of 8 month duration. He was a diagnosed case of compensated chronic hepatitis C and had received interferon Alfa therapy before. Fundus examination of both eye showed multiple hard exudates at macula with a plaque involving the foveal center in right eye. OCT and FFA confirmed the findings seen clinically. Patient was advised regular follow up and on 3 months follow up his clinical picture was same. Ours is the first case report where patient had significant visual loss secondary to hard exudate plaque at center of fovea and ischemic fovea in right eye.Presence of hard exudates at any stage of therapy of hepatitis C could be an indicator of the severity of retinopathy with possible indication for stopping the drug.


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