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REVIEW ARTICLE
Year : 2015  |  Volume : 8  |  Issue : 2  |  Page : 86-91

Corneal cross-linking treatment of keratoconus


Department of Cornea, Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Dr. Mohammad Naderan
Eye Research Center, Farabi Eye Hospital, Qazvin Square, Tehran
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-620X.159105

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Keratoconus as the most common cause of ectasia is one of the leading cause of corneal transplants worldwide. The current available therapies do not modify the underlying pathogenesis of the disease, and none of the available approaches but corneal transplant hinder the ongoing ectasia. Several studies document Crosslink defect between collagen fibrils in the pathogenesis of keratoconus. Collagen cross link is a relatively new approach that with the application of the riboflavin and ultraviolet A, new covalent bands reform. Subjective and objective results following this method seem to be promising. Endothelial damage besides other deep structural injury, which is the major concern of this technique have not yet been reported, when applying the standard method.


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