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CASE REPORT
Year : 2014  |  Volume : 7  |  Issue : 2  |  Page : 81-83

Giant leiomyoma of the ciliary body


1 Department of Ocular Oncology, Wills Eye Institute, Thomas Jefferson University, 840 Walnut Street, 14th Floor, Philadelphia PA, 19107
2 Department of Ocular Oncology; Department of Pathology, Wills Eye Institute, Thomas Jefferson University, 840 Walnut Street, 14th Floor, Philadelphia PA, 19107
3 Department of Pathology, Wills Eye Institute, Thomas Jefferson University, 840 Walnut Street, 14th Floor, Philadelphia PA, 19107

Correspondence Address:
Carol L Shields
Ocular Oncology Service, 840 Walnut Street, Suite 1440, Philadelphia, PA 19107

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Source of Support: Lift for a Cure, Morrisdale, PA (CLS), Mellon Charitable Giving from the Martha W. Rogers Charitable Trust, Philadelphia, PA (CLS), the Eye Tumor Research Foundation, Philadelphia, PA (CLS, JAS). Carol L. Shields, M.D. has had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis., Conflict of Interest: None


DOI: 10.4103/0974-620X.137165

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Leiomyoma is a rare intraocular tumor that arises from uveal smooth muscle. Herein, we report a large leiomyoma that occupied nearly 50% of the globe, closely resembling melanoma. A 40-year-old female presented with a 17 x 15 x 11 mm amelanotic ciliochoroidal mass causing visual defect in her right eye (OD). Based on transillumination features of tumor shadow and ultrasonographic features of acoustically solid mass, there was low clinical suspicion for leiomyoma or schwannoma, and a preliminary diagnosis of ciliochoroidal melanoma was rendered. Following enucleation, histopathology revealed a paucicellular tumor comprised of spindle cells, with positive immunostaining for smooth muscle actin and negative stains for melanoma markers (S-100 protein, HMB45, and MITF-2). These features were consistent with ciliochoroidal leiomyoma. Benign uveal leiomyoma can achieve an unusually large size and block light transmission on transillumination, features that simulate malignant melanoma.


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